For casual or tourney play?
For casual play, threshold has become pretty much par for the course in our group - as has the Graveyard hate.
For T1 tourney play, I don't think it has had much of an effect, although Barbarian Ring and Cephalid Colloseum have have a little impact. Any deck that runs Timetwister would probably not even consider threshold. There are a few cards that I feel could have an impact though down the road (but I'm no expert):
Hunting Grounds - Its useless w/o threshold, but considering how easy it is to get 7 cards in the GY in Type 1 does it matter? This card has a near broken ability once it gets going, and I don't see why the type 2 snake lock-down deck can't get even better in T1 (although it loses 3 Fact or Fiction). Of course its GW which is the least popular color combo in T1.
Lightning Suge - Its very expensive, but there is not too much red burn that can't be prevented. Of course a red spell this expensive belongs in a control deck, and there aren't too many red control decks.
Mystic Enforcer - Protection from Abyss, can't be killed by a Morphling, big and cheap flyer. But again, GW
Nantuko Monastery - In the right deck this card can be a house in T1, GW or not. Its biggest weakness is how much land hate is around.
Rancid Earth - Black LD decks are still around, this is one of the better black LD spells.