It's mostly no problem if it's removed. It can potentially lead to bowel obstructions. This is not because the appendix is missing, but because intrusive surgeries in which the bowels are handled can cause obstructions.
Regrowth might work, although with the percentage of cards in this deck that are permanents, it's likely a dead card if you draw it early game and don't get hit by removal...
What white creatures did you have in mind? Something like Monk Idealist?