Yeah. Muzzle, pacifism, arrest, and cessation can make for a slow game. I played Nanokill's rapid angel deck with a deck using those. It went somehting like this:
Him:Cast blinding angel
Me: Muzzle it
Him: Cast Serra Angel
Me: Pacifism it
Him: Cast Radiant
Me: Arrest it
Him: Dammit! Cast Serra!
Me: Pacifism it
Him: Dammit dammit! Cast Blinding angel!
Me: Cessation it
Him: Dammit Dammit Dammit!
He eventually won, but it was fun while it lasted.